5362/10 | Tocris Bioscience 5362/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

5362/10

catalog :

5362/10

quantity :

10 mg (also 50 mg)

price :

226 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 5362 - TASP 0433864 C18H23N3O3 CAS No. 1431980-60-7

product information

master code :

5362

SKU :

5362/10

product name :

TASP 0433864

unit size :

10 mg (also 50 mg)

description :

Selective positive allosteric modulator of mGlu2 receptors

target :

Group II mGluR Modulators

category :

Small Molecules

purity :

98%

observed molecular weight :

329.39

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

TASP 0433864 is a selective mGlu2 receptor positive allosteric modulator (EC50 values are 199 and 206 nM for human and rat receptors, respectively). Exhibits negligible activity against a range of neurotransmitter targets, except 5-HT2B and MAO-B (72 and 92% inhibition at 10 M, respectively). Potentiates inhibitory effect of DCG IV (Cat. No. 0975) on excitatory postsynaptic potentials in hippocampal slices and ketamine- and methamphetamine-induced increases in locomotor activity in rats and mice.

top caption :

Selective positive allosteric modulator of mGlu2 receptors

extended description :

Selective positive allosteric modulator of mGlu2 receptors

chemical name text :

(2S)-2-[[4-(1,1-Dimethylethyl)phenoxy]methyl]-2,3-dihydro-5-methylimidazo[2,1-b]oxazole-6-carboxamide

formula :

C18H23N3O3

formula text :

C18H23N3O3

cas num :

1431980-60-7

USD :

226 USD

product details :

Selective positive allosteric modulator of mGlu2 receptors

storage :

Store at +4░C

more info or order :

Tocris Bioscience product webpage