Cariporide | Tocris Bioscience 5358 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Cariporide

catalog :

5358

quantity :

10 mg (also 50 mg)

price :

113 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

5358

SKU :

5358/10

product name :

Cariporide

description :

Selective NHE1 inhibitor; cardioprotective and antitumor

target :

Na+/H+ Exchanger Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

283.35

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Selective Na+/H+ exchanger isoform 1 (NHE1) inhibitor (IC50 values are 0.05, 3 and 1000 M for NHE1, NHE3 and NHE2 respectively). Attenuates ischemia-induced cardiomyocyte apoptosis in vitro . Reduces cardiac arrhythmia in vivo . Also promotes apoptosis in cancer cells overexpressing NHE1. Orally active.

catalog number base :

5358

product keywords :

Cariporide HOE642 selective sodium hydrogen exchanger NHE1 inhibitors inhibits cardioprotective cardiomyocytes ischemia orally active Na+/H+ HOE 642 Na+/H+ Exchanger 5358,

extended description :

Selective NHE1 inhibitor; cardioprotective and antitumor

chemical name text :

N-(Aminoiminomethyl)-4-(1-methylethyl)-3-(methylsulfonyl)benzamide

formula :

C 12 H 17 N 3 O 3 S

formula text :

C12H17N3O3S

cas num :

159138-80-4

2020 USD :

109

2021 USD :

113 USD

alt names :

HOE 642

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage