SGX 523 | Tocris Bioscience 5356 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

SGX 523

catalog :

5356

quantity :

10 mg (also 50 mg)

price :

279 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Bastounis E, Yeh Y, Theriot J. Matrix stiffness modulates infection of endothelial cells by Listeria monocytogenes via expression of cell surface vimentin. Mol Biol Cell. 2018;29:1571-1589 pubmed publisher
Ortega F, Rengarajan M, Chavez N, Radhakrishnan P, Gloerich M, Bianchini J, et al. Adhesion to the host cell surface is sufficient to mediate Listeria monocytogenes entry into epithelial cells. Mol Biol Cell. 2017;28:2945-2957 pubmed publisher

product information

brand :

Tocris

master code :

5356

SKU :

5356/10

product name :

SGX 523

description :

Selective and potent c-MET kinase inhibitor

target :

MET Receptor Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

99%

observed molecular weight :

359.41

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent and selective c-MET kinase inhibitor (IC50 = 4nM). Exhibits minimal inhibition against a panel of 213 other protein kinases (at 1 M). Suppresses growth of tumor xenografts derived from human glioblastoma, lung and gastric cancer cells.

catalog number base :

5356

product keywords :

SGX523 Selective potent c-MET kinase inhibitors inhibits MET Receptors 5356,

extended description :

Selective and potent c-MET kinase inhibitor

chemical name text :

6-[[6-(1-Methyl-1H-pyrazol-4-yl)-1,2,4-triazolo[4,3-b]pyridazin-3-yl]thio]quinoline

formula :

C 18 H 13 N 7 S

formula text :

C18H13N7S

cas num :

1022150-57-7

2020 USD :

270

2021 USD :

279 USD

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage