5356/10 | Tocris Bioscience 5356/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

5356/10

catalog :

5356/10

quantity :

10 mg (also 50 mg)

price :

312 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Bastounis E, Yeh Y, Theriot J. Matrix stiffness modulates infection of endothelial cells by Listeria monocytogenes via expression of cell surface vimentin. Mol Biol Cell. 2018;29:1571-1589 pubmed publisher
Ortega F, Rengarajan M, Chavez N, Radhakrishnan P, Gloerich M, Bianchini J, et al. Adhesion to the host cell surface is sufficient to mediate Listeria monocytogenes entry into epithelial cells. Mol Biol Cell. 2017;28:2945-2957 pubmed publisher

image

image 1 :

Cat.No. 5356 - SGX 523 C18H13N7S CAS No. 1022150-57-7

product information

master code :

5356

SKU :

5356/10

product name :

SGX 523

unit size :

10 mg (also 50 mg)

description :

Selective and potent c-MET kinase inhibitor

target :

MET Receptor Inhibitors

category :

Small Molecules

purity :

99%

observed molecular weight :

359.41

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

SGX 523 is a potent and selective c-MET kinase inhibitor (IC50 = 4nM). Exhibits minimal inhibition against a panel of 213 other protein kinases (at 1 M). Suppresses growth of tumor xenografts derived from human glioblastoma, lung and gastric cancer cells.

top caption :

Selective and potent c-MET kinase inhibitor

extended description :

Selective and potent c-MET kinase inhibitor

chemical name text :

6-[[6-(1-Methyl-1H-pyrazol-4-yl)-1,2,4-triazolo[4,3-b]pyridazin-3-yl]thio]quinoline

formula :

C18H13N7S

formula text :

C18H13N7S

cas num :

1022150-57-7

USD :

312 USD

product details :

Selective and potent c-MET kinase inhibitor

storage :

Store at +4░C

more info or order :

Tocris Bioscience product webpage