Gap19 | Tocris Bioscience 5353 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Gap19

catalog :

5353

quantity :

1 mg

price :

227 USD

more info or order :

Tocris Bioscience product webpage

citations: 3

Reference
Best S, Ding S, Kersbergen A, Dong X, Song J, Xie Y, et al. Distinct initiating events underpin the immune and metabolic heterogeneity of KRAS-mutant lung adenocarcinoma. Nat Commun. 2019;10:4190 pubmed publisher
Chen Y, Wang L, Zhang L, Chen B, Yang L, Li X, et al. Inhibition of Connexin 43 Hemichannels Alleviates Cerebral Ischemia/Reperfusion Injury via the TLR4 Signaling Pathway. Front Cell Neurosci. 2018;12:372 pubmed publisher
Almad A, Doreswamy A, Gross S, Richard J, Huo Y, Haughey N, et al. Connexin 43 in astrocytes contributes to motor neuron toxicity in amyotrophic lateral sclerosis. Glia. 2016;64:1154-69 pubmed publisher

product information

brand :

Tocris

master code :

5353

SKU :

5353/1

product name :

Gap19

description :

Cx43 hemichannel blocker

target :

Gap Channel Blockers

category :

Peptides

unit size :

1 mg

observed molecular weight :

1161.45

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=peptides

details of functionality :

Selective connexin 43 (Cx43) hemichannel blocker; has no effect on gap junction coupling or Panx-1 channels. Reduces mitochondrial potassium influx in cardiomyocytes and attenuates glutamate-triggered ATP release in primary astrocytes. Modestly reduces infarct size in a mouse ischemia model.

catalog number base :

5353

product keywords :

Selective Cx43 hemichannels blockers blocks Connexin43 Panx-1 gap junctions Gap Channels 5353,

extended description :

Cx43 hemichannel blocker

formula :

C 55 H 96 N 14 O 13

formula text :

C55H96N14O13

cas num :

1507930-57-5

2020 USD :

218

2021 USD :

227 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage