ML 348 | Tocris Bioscience 5345 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

ML 348

catalog :

5345

quantity :

10 mg (also 50 mg)

price :

208 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Zingler P, Särchen V, Glatter T, Caning L, Saggau C, Kathayat R, et al. Palmitoylation is required for TNF-R1 signaling. Cell Commun Signal. 2019;17:90 pubmed publisher
Vujic I, Sanlorenzo M, Esteve Puig R, Vujic M, Kwong A, Tsumura A, et al. Acyl protein thioesterase 1 and 2 (APT-1, APT-2) inhibitors palmostatin B, ML348 and ML349 have different effects on NRAS mutant melanoma cells. Oncotarget. 2016;7:7297-306 pubmed publisher

product information

brand :

Tocris

master code :

5345

SKU :

5345/10

product name :

ML 348

description :

Selective and reversible lysophospholipase 1 (LYPLA1) inhibitor

target :

Hydrolase Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

99%

observed molecular weight :

415.79

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Selective and reversible lysophospholipase 1 (LYPLA1) inhibitor (IC50 = 210 nM). Exhibits 14-fold selectivity for LYPLA1 over LYPLA2. Also selective over a panel of ~30 other serine hydrolases.

catalog number base :

5345

product keywords :

ML348 selective reversible lysophospholipase 1 lypla1 inhibitors inhibits APT1 acyl protein thioesterase 1 Other Hydrolases 5345,

extended description :

Selective and reversible lysophospholipase 1 (LYPLA1) inhibitor

chemical name text :

N-[2-Chloro-5-(trifluoromethyl)phenyl]-4-(2-furanylcarbonyl)-1-piperazineacetamide

formula :

C 18 H 17 ClF 3 N 3 O 3

formula text :

C18H17ClF3N3O3

cas num :

899713-86-1

2020 USD :

201

2021 USD :

208 USD

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage