ML 349 | Tocris Bioscience 5344 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

ML 349

catalog :

5344

quantity :

10 mg (also 50 mg)

price :

223 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Zingler P, Särchen V, Glatter T, Caning L, Saggau C, Kathayat R, et al. Palmitoylation is required for TNF-R1 signaling. Cell Commun Signal. 2019;17:90 pubmed publisher
Vujic I, Sanlorenzo M, Esteve Puig R, Vujic M, Kwong A, Tsumura A, et al. Acyl protein thioesterase 1 and 2 (APT-1, APT-2) inhibitors palmostatin B, ML348 and ML349 have different effects on NRAS mutant melanoma cells. Oncotarget. 2016;7:7297-306 pubmed publisher

product information

brand :

Tocris

master code :

5344

SKU :

5344/10

product name :

ML 349

description :

Selective and reversible lysophospholipase 2 (LYPLA2) inhibitor

target :

Hydrolase Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

454.56

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Selective and reversible lysophospholipase 2 (LYPLA2) inhibitor (IC50 = 144 nM). Displays selectively over LYPLA1 and 20 other serine hydrolases (IC50 values are 3000 and 10,000 nM respectively).

catalog number base :

5344

product keywords :

ML349 selective reversible Lysophospholipase 2 LYPLA2 inhibitors inhibits serine hydrolases APT2 protein acyl thioesterase 2 Other Hydrolases 5344,

extended description :

Selective and reversible lysophospholipase 2 (LYPLA2) inhibitor

chemical name text :

(5,5-Dioxido-4H-thieno[3,2-c][1]benzothiopyran-2-yl)[4-(4-methoxyphenyl)-1-piperazinyl]methanone

formula :

C 23 H 22 N 2 O 4 S 2

formula text :

C23H22N2O4S2

cas num :

890819-86-0

2020 USD :

214

2021 USD :

223 USD

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage