TPPB | Tocris Bioscience 5343 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

TPPB

catalog :

5343

quantity :

1 mg

price :

145 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Yang L, Han Y, Nilsson Payant B, Gupta V, Wang P, Duan X, et al. A Human Pluripotent Stem Cell-based Platform to Study SARS-CoV-2 Tropism and Model Virus Infection in Human Cells and Organoids. Cell Stem Cell. 2020;27:125-136.e7 pubmed publisher

product information

brand :

Tocris

master code :

5343

SKU :

5343/1

product name :

TPPB

description :

High affinity PKC activator; also APP modulator

target :

Protein Kinase C Activators

category :

Small Molecules

unit size :

1 mg

purity :

98%

observed molecular weight :

501.54

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

High affinity protein kinase C activator (Ki =11.9 nM). Induces differentiation of hESCs into Pdx-1 expressing pancreatic progenitor cells. Also enhances secretion of amyloid precursor protein. Cell permeable.

catalog number base :

5343

product keywords :

PKC activator high affinity induces differentiation Pdx-1 pancreatic progenitor amyloid precursor protein cell permeable APP Protein Kinase C Other Differentiation Products Amyloid Beta Peptides 5343,

extended description :

High affinity PKC activator; also APP modulator

chemical name text :

(2E,4E)-N-[(2S,5S)-1,2,3,4,5,6-Hexahydro-5-(hydroxymethyl)-1-methyl-2-(1-methylethyl)-3-oxo-1,4-benzodiazocin-8-yl]-5-[4-(trifluoromethyl)phenyl]-2,4-pentadienamide

formula :

C 27 H 30 F 3 N 3 O 3

formula text :

C27H30F3N3O3

cas num :

497259-23-1

2020 USD :

142

2021 USD :

145 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage