NSC 617145 | Tocris Bioscience 5340/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

NSC 617145

catalog :

5340/10

quantity :

10 mg (also 50 mg)

price :

195 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Datta A, Biswas K, Sommers J, Thompson H, Awate S, Nicolae C, et al. WRN helicase safeguards deprotected replication forks in BRCA2-mutated cancer cells. Nat Commun. 2021;12:6561 pubmed publisher

product information

brand :

Tocris

master code :

5340

SKU :

5340/10

product name :

NSC 617145

unit size :

10 mg (also 50 mg)

seo description :

Werner syndrome helicase (WRN) inhibitor

target :

DNA, RNA and Protein Synthesis Inhibitors

category :

Small Molecules

purity :

98%

observed molecular weight :

400.04

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

NSC 617145 is a werner syndrome helicase (WRN) helicase inhibitor (IC50 = 250 nM); acts synergistically with Mitomycin C (Cat. No. 3258) to induce double-strand breaks and chromosomal abnormalities in vitro .

top caption :

Werner syndrome helicase (WRN) inhibitor

extended description :

Werner syndrome helicase (WRN) inhibitor

chemical name text :

1,1 -(2,2-Dimethyl-1,3-propanediyl)bis[3,4-dichloro-1H-pyrrole-2,5-dione

formula :

C13H10Cl4N2O4

formula text :

C13H10Cl4N2O4

cas num :

203115-63-3

USD :

195 USD

product details :

Werner syndrome helicase (WRN) inhibitor

storage :

Store at -20░C

more info or order :

Tocris Bioscience product webpage