PFK 15 | Tocris Bioscience 5339/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

PFK 15

catalog :

5339/10

quantity :

10 mg (also 50 mg)

price :

182 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 5339 - PFK 15 C17H12N2O CAS No. 4382-63-2

product information

brand :

Tocris

master code :

5339

SKU :

5339/10

product name :

PFK 15

unit size :

10 mg (also 50 mg)

seo description :

Selective PFKFB3 inhibitor

target :

PFKFB3 Inhibitors

category :

Small Molecules

purity :

99%

observed molecular weight :

260.29

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

PFK 15 is originally reported to be a selective PFKFB3 inhibitor (IC50 = 207 nM); a more recent report failed to demonstrate activity in a PFKFB3 kinase assay. Selective for PFKFB3 over a panel of 96 kinases. Reduces glucose uptake and induces apoptosis in H522 lung adenocarcinoma and Jurkat T cell leukemia cells. Suppresses glucose uptake and tumor growth, and inhibits metastasis of Lewis lung carcinoma cell xenografts in mice.

top caption :

Selective PFKFB3 inhibitor

extended description :

Selective PFKFB3 inhibitor

chemical name text :

1-(4-Pyridinyl)-3-(2-quinolinyl)-2-propen-1-one

formula :

C17H12N2O

formula text :

C17H12N2O

cas num :

4382-63-2

USD :

182 USD

product details :

Selective PFKFB3 inhibitor

storage :

Store at -20░C

more info or order :

Tocris Bioscience product webpage