PK-THPP | Tocris Bioscience 5338 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

PK-THPP

catalog :

5338

quantity :

10 mg (also 50 mg)

price :

219 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Veldkamp M, Geuzebroek G, Baartscheer A, Verkerk A, Schumacher C, Suarez G, et al. Neurokinin-3 receptor activation selectively prolongs atrial refractoriness by inhibition of a background K+ channel. Nat Commun. 2018;9:4357 pubmed publisher

product information

brand :

Tocris

master code :

5338

SKU :

5338/10

product name :

PK-THPP

description :

Potent K2P9.1 (TASK-3) channel blocker

target :

Two-P Potassium Channels Blockers

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

99%

observed molecular weight :

468.59

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent TASK-3 channel blocker (IC50 = 35 and 300 nM for TASK-3 and TASK-1 respectively). Increases breathing rate and induces respiratory alkalosis in rats.

catalog number base :

5338

product keywords :

potent TASK3 channels blockers TWIK related acid sensitive K+ two pore potassium potassium K2P9.1 subfamily member 9 Two-P Potassium Channels 5338,

extended description :

Potent K2P9.1 (TASK-3) channel blocker

chemical name text :

1-[1-[6-[[1,1 -Biphenyl]-4-ylcarbonyl)-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-4-yl]-4-piperidinyl]-1-butanone

formula :

C 29 H 32 N 4 O 2

formula text :

C29H32N4O2

cas num :

1332454-07-5

2020 USD :

212

2021 USD :

219 USD

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage