PK-THPP | Tocris Bioscience 5338/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

PK-THPP

catalog :

5338/10

quantity :

10 mg (also 50 mg)

price :

276 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Veldkamp M, Geuzebroek G, Baartscheer A, Verkerk A, Schumacher C, Suarez G, et al. Neurokinin-3 receptor activation selectively prolongs atrial refractoriness by inhibition of a background K+ channel. Nat Commun. 2018;9:4357 pubmed publisher

image

image 1 :

Cat.No. 5338 - PK-THPP C29H32N4O2 CAS No. 1332454-07-5

product information

brand :

Tocris

master code :

5338

SKU :

5338/10

product name :

PK-THPP

unit size :

10 mg (also 50 mg)

seo description :

Potent K2P9.1 (TASK-3) channel blocker

target :

Two-P Potassium Channels Blockers

category :

Small Molecules

purity :

99%

observed molecular weight :

468.59

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

PK-THPP is a potent TASK-3 channel blocker (IC50 = 35 and 300 nM for TASK-3 and TASK-1 respectively). Increases breathing rate and induces respiratory alkalosis in rats.

top caption :

Potent K2P9.1 (TASK-3) channel blocker

extended description :

Potent K2P9.1 (TASK-3) channel blocker

chemical name text :

1-[1-[6-[[1,1 -Biphenyl]-4-ylcarbonyl)-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-4-yl]-4-piperidinyl]-1-butanone

formula :

C29H32N4O2

formula text :

C29H32N4O2

cas num :

1332454-07-5

USD :

276 USD

product details :

Potent K2P9.1 (TASK-3) channel blocker

storage :

Store at +4░C

more info or order :

Tocris Bioscience product webpage