Rosiglitazone | Tocris Bioscience 5325 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Rosiglitazone

catalog :

5325

quantity :

10 mg (also 50 mg)

price :

71 USD

more info or order :

Tocris Bioscience product webpage

citations: 7

Reference
Fellous T, De Maio F, Kalkan H, Carannante B, Boccella S, Petrosino S, et al. Phytocannabinoids promote viability and functional adipogenesis of bone marrow-derived mesenchymal stem cells through different molecular targets. Biochem Pharmacol. 2020;175:113859 pubmed publisher
Smith D, Martinelli R, Besra G, Illarionov P, Szatmari I, Brazda P, et al. Identification and characterization of a novel anti-inflammatory lipid isolated from Mycobacterium vaccae, a soil-derived bacterium with immunoregulatory and stress resilience properties. Psychopharmacology (Berl). 2019;: pubmed publisher
Brust R, Shang J, Fuhrmann J, Mosure S, Bass J, Cano A, et al. A structural mechanism for directing corepressor-selective inverse agonism of PPARγ. Nat Commun. 2018;9:4687 pubmed publisher
Vitale R, D Aniello E, Gorbi S, Martella A, Silvestri C, Giuliani M, et al. Fishing for Targets of Alien Metabolites: A Novel Peroxisome Proliferator-Activated Receptor (PPAR) Agonist from a Marine Pest. Mar Drugs. 2018;16: pubmed publisher
Warrick J, Walter V, Yamashita H, Chung E, Shuman L, Amponsa V, et al. FOXA1, GATA3 and PPAR? Cooperate to Drive Luminal Subtype in Bladder Cancer: A Molecular Analysis of Established Human Cell Lines. Sci Rep. 2016;6:38531 pubmed publisher
Matsa E, Burridge P, Yu K, Ahrens J, Termglinchan V, Wu H, et al. Transcriptome Profiling of Patient-Specific Human iPSC-Cardiomyocytes Predicts Individual Drug Safety and Efficacy Responses InÂ Vitro. Cell Stem Cell. 2016;19:311-25 pubmed publisher
Ahlem C, Kennedy M, Page T, Reading C, White S, McKenzie J, et al. Studies of the pharmacology of 17?-ethynyl-androst-5-ene-3?,7?,17?-triol, a synthetic anti-inflammatory androstene. Int J Clin Exp Med. 2011;4:119-35 pubmed

product information

brand :

Tocris

master code :

5325

SKU :

5325/10

product name :

Rosiglitazone

description :

Potent and selective PPAR agonist; antidiabetic agent

target :

PPAR gamma Receptor Agonists

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

99%

observed molecular weight :

357.43

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent and selective PPAR agonist (EC50 = 60 nM); exhibits no activity at PPAR and PPAR . Promotes differentiation of pluripotent C3H10T1/2 stem cells into adipocytes. Also promotes differentiation of urothelial organoids in combination with erlotinib. Exhibits antihyperglycemic activity in diabetic ob/ob mouse model. Antidiabetic agent.

catalog number base :

5325

product keywords :

BRL49653 High affinity selective PPAR agonist thiazolidinedione TZD derivative antidiabetic agent organoids differentiation BRL 49653 PPARgamma Receptors Other Differentiation Products Organoids 5325,

extended description :

Potent and selective PPAR agonist; antidiabetic agent

chemical name text :

5-[[4-[2-(Methyl-2-pyridinylamino)ethoxy]phenyl]methyl]-2,4-thiazolidinedione

formula :

C 18 H 19 N 3 O 3 S

formula text :

C18H19N3O3S

cas num :

122320-73-4

2020 USD :

2021 USD :

71 USD

alt names :

BRL 49653

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage