VU 0409106 | Tocris Bioscience 5322 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

VU 0409106

catalog :

5322

quantity :

10 mg (also 50 mg)

price :

164 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

5322

SKU :

5322/10

product name :

VU 0409106

description :

Potent and selective negative allosteric modulator of mGlu5 receptors

target :

Group I mGluR Modulators

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

330.34

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent and selective mGlu5 negative allosteric modulator (IC50 = 49 nM at human mGlu5). Selective for mGlu5 over a panel of GPCRs and ion channels. Exhibits no significant nonspecific binding in rat brain homogenates in vitro . Inhibits marble burying behavior in mice. Brain penetrant.

catalog number base :

5322

product keywords :

VU0409106 metabotropic glutamate receptors negative allosteric modulators NAMs mGluR5 class I Glutamate (Metabotropic) Group I Receptors 5322,

extended description :

Potent and selective negative allosteric modulator of mGlu5 receptors

chemical name text :

3-Fluoro-N-(4-methyl-2-thiazolyl)-5-(5-pyrimidinyloxy)benzamide

formula :

C 15 H 11 FN 4 O 2 S

formula text :

C15H11FN4O2S

cas num :

1276617-62-9

2020 USD :

164

2021 USD :

164 USD

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage