ACT 462206 | Tocris Bioscience 5319/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

ACT 462206

catalog :

5319/10

quantity :

10 mg (also 50 mg)

price :

245 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Parekh R, White A, Leffler K, Biancardi V, Eells J, Abdel Rahman A, et al. Hypothalamic kinin B1 receptor mediates orexin system hyperactivity in neurogenic hypertension. Sci Rep. 2021;11:21050 pubmed publisher

image

image 1 :

Cat.No. 5319 - ACT 462206 C20H24N2O4S CAS No. 1361321-96-1

product information

brand :

Tocris

master code :

5319

SKU :

5319/10

product name :

ACT 462206

unit size :

10 mg (also 50 mg)

seo description :

Potent, dual orexin receptor antagonist

target :

Orexin Receptor Antagonists

category :

Small Molecules

purity :

99%

observed molecular weight :

388.48

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

ACT 462206 is a potent, dual orexin receptor antagonist (IC50 values are 11 and 60 nM for OX2 and OX1 receptors respectively). Exhibits anxiolytic-like properties in vivo . Brain penetrant.

top caption :

Potent, dual orexin receptor antagonist

extended description :

Potent, dual orexin receptor antagonist

chemical name text :

(2S)-N-(3,5-Dimethylphenyl)-1-[(4-methoxyphenyl)sulfonyl]-2-pyrrolidinecarboxamide

formula :

C20H24N2O4S

formula text :

C20H24N2O4S

cas num :

1361321-96-1

USD :

245 USD

product details :

Potent, dual orexin receptor antagonist

storage :

Store at +4░C

more info or order :

Tocris Bioscience product webpage