LY 315920 | Tocris Bioscience 5313/50 product information

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product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

LY 315920

catalog :

5313/50

quantity :

50 mg

price :

805 USD

product information

CHEMISTRY :

OC(COC1=C2C(N(CC3=CC=CC=C3)C(CC)=C2C(C(N)=O)=O)=CC=C1)=O

Stock Reference :

5313/50

Cat Number :

5313

Product Name :

LY 315920

Cas Number :

[172732-68-2]

Unit Size :

50 mg

Size :

Unit :

USD :

805 USD

Primary Category :

Enzymes

Secondary Category :

Esterases

Tertiary Category :

Phospholipases

Primary Action :

Selective secreted phospholipase A2 (sPLA2) inhibitor

Biological Description :

Selective secreted phospholipase A2 (sPLA2) inhibitor (IC50 = 50 - 750 nM for a range of sPLA2 isoforms). Has no effect on cytosolic PLA2 or COX-1 and COX-2 activity. Attenuates sPLA2-induced thromboxane formation in bronchoalveolar lavage (BAL) cells. Also suppresses sPLA2-induced contractions of lung pleural strips ex vivo. Orally available.

Storage :

Store at -20°C

Formula :

C21H20N2O5

Molwt :

380.39

Minimum Purity :

> 98%

Solubility :

Soluble to 100 mM in DMSO

RTECS No :

Not available

Synonyms :

Varespladib