ASP 3026 | Tocris Bioscience 5310/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

ASP 3026

catalog :

5310/10

quantity :

10 mg (also 50 mg)

price :

208 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 5310 - ASP 3026 C29H40N8O3S CAS No. 1097917-15-1

product information

brand :

Tocris

master code :

5310

SKU :

5310/10

product name :

ASP 3026

unit size :

10 mg (also 50 mg)

seo description :

Potent anaplastic lymphoma kinase (ALK) inhibitor; also potent ACK inhibitor

target :

ALK Inhibitors

category :

Small Molecules

purity :

99%

observed molecular weight :

580.74

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

ASP 3026 is a potent anaplastic lymphoma kinase (ALK) inhibitor (IC50 = 3.5 nM). Also inhibits Ack and ROS1 activity (IC50 values are 5.8 and 8.9 nM respectively). Attenuates proliferation, and induces apoptosis of NPM-ALK+ T cell anaplastic large-cell lymphoma (ALCL) cells in vitro . Suppresses tumor growth of NPM-ALK+ ALCL cell xenografts in mice. Causes tumor shrinkage in hEML4-ALK transgenic mice. Orally available.

top caption :

Potent anaplastic lymphoma kinase (ALK) inhibitor; also potent ACK inhibitor

extended description :

Potent anaplastic lymphoma kinase (ALK) inhibitor; also potent ACK inhibitor

chemical name text :

N2-[2-Methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]-N4-[2-[(1-methylethyl)sulfonyl]phenyl]-1,3,5-triazine-2,4-diamine

formula :

C29H40N8O3S

formula text :

C29H40N8O3S

cas num :

1097917-15-1

USD :

208 USD

product details :

Potent anaplastic lymphoma kinase (ALK) inhibitor; also potent ACK inhibitor

storage :

Store at -20░C

more info or order :

Tocris Bioscience product webpage