ASP 2535 | Tocris Bioscience 5308 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

ASP 2535

catalog :

5308

quantity :

10 mg

price :

262 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Ostrovskaya R, Vakhitova Y, Kuzmina U, Salimgareeva M, Zainullina L, Gudasheva T, et al. Neuroprotective effect of novel cognitive enhancer noopept on AD-related cellular model involves the attenuation of apoptosis and tau hyperphosphorylation. J Biomed Sci. 2014;21:74 pubmed publisher

product information

brand :

Tocris

master code :

5308

SKU :

5308/10

product name :

ASP 2535

description :

Potent and selective GlyT1 inhibitor

target :

Glycine Transporter Inhibitors

category :

Small Molecules

unit size :

10 mg

purity :

98%

observed molecular weight :

382.42

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent and selective GlyT1 inhibitor (IC50 = 92 nM). Exhibits 50-fold selectivity over GlyT2. Attenuates MK 801 -induced working memory deficits and PCP -induced visual learning deficits in mice. Orally available and brain penetrant.

catalog number base :

5308

product keywords :

ASP2535 potent selective glycine transporters GlyT1 inhibitors inhibits schizophrenia alzheimer s disease Glycine Transporters 5308,

extended description :

Potent and selective GlyT1 inhibitor

chemical name text :

4-[3-(1-Methylethyl)-5-(6-phenyl-3-pyridinyl)-4H-1,2,4-triazol-4-yl]-2,1,3-benzoxadiazole

formula :

C 22 H 18 N 6 O

formula text :

C22H18N6O

cas num :

374886-51-8

2020 USD :

254

2021 USD :

262 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage