product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
ASP 2535
catalog :
5308/10
quantity :
10 mg
price :
330 USD
more info or order :
citations: 1
Reference
Ostrovskaya R, Vakhitova Y, Kuzmina U, Salimgareeva M, Zainullina L, Gudasheva T, et al. Neuroprotective effect of novel cognitive enhancer noopept on AD-related cellular model involves the attenuation of apoptosis and tau hyperphosphorylation. J Biomed Sci. 2014;21:74 pubmed publisher
image
image 1 :
Tocris Bioscience 5308/10 image 1
Cat.No. 5308 - ASP 2535 C22H18N6O CAS No. 374886-51-8
product information
brand :
Tocris
master code :
5308
SKU :
5308/10
product name :
ASP 2535
unit size :
10 mg
seo description :
Potent and selective GlyT1 inhibitor
target :
Glycine Transporter Inhibitors
category :
Small Molecules
purity :
98%
observed molecular weight :
382.42
url print :
?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
ASP 2535 is a potent and selective GlyT1 inhibitor (IC50 = 92 nM). Exhibits 50-fold selectivity over GlyT2. Attenuates MK 801 -induced working memory deficits and PCP -induced visual learning deficits in mice. Orally available and brain penetrant.
top caption :
Potent and selective GlyT1 inhibitor
extended description :
Potent and selective GlyT1 inhibitor
chemical name text :
4-[3-(1-Methylethyl)-5-(6-phenyl-3-pyridinyl)-4H-1,2,4-triazol-4-yl]-2,1,3-benzoxadiazole
formula :
C22H18N6O
formula text :
C22H18N6O
cas num :
374886-51-8
USD :
330 USD
product details :
Potent and selective GlyT1 inhibitor
storage :
Store at -20░C
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK