product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
MM 102
catalog :
5307
quantity :
10 mg
price :
278 USD
more info or order :
Tocris Bioscience product webpage
product information
brand :
Tocris
master code :
5307
SKU :
5307/10
product name :
MM 102
description :
Potent WDR5/MLL interaction inhibitor
target :
Lysine Methyltransferase Inhibitors
category :
Small Molecules
unit size :
10 mg
purity :
98%
observed molecular weight :
783.83
url print :
?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
Potent WDR5/MLL interaction inhibitor (IC50 = 2.4 nM). Inhibits MLL1 methyltransferase activity and MLL-1-induced HoxA9 and Meis-1 gene expression in leukemia cells expressing the MLL1-AF9 fusion gene. Also inhibits cell growth and induces apoptosis in leukemia cells harbouring MLL1 fusion proteins.
catalog number base :
5307
product keywords :
MM102 Mixed lineage leukemia 1 MLL1 WD repeat-containing protein 5 WDR5 interaction inhibitors inhibits leukemia leukaemia 14173292483 1417329_24_83 Lysine Methyltransferases WDR5 5307,
extended description :
Potent WDR5/MLL interaction inhibitor
chemical name text :
1-[[(2S)-5-[(Aminoiminomethyl)amino]-2-[[2-ethyl-2-[(2-methyl-1-oxopropyl)amino]-1-oxobutyl]amino]-1-oxopentyl]amino]-N-[bis(4-fluorophenyl)methyl]-cyclopentanecarboxamide trifluoroacetate
formula :
C 35 H 49 F 2 N 7 O 4 .CF 3 CO 2 H
formula text :
C35H49F2N7O4.CF3CO2H
cas num :
1883545-52-5
2020 USD :
267
2021 USD :
278 USD
storage :
Store at -20°C
more info or order :
Tocris Bioscience product webpage
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK