GSK 2194069 | Tocris Bioscience 5303 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

GSK 2194069

catalog :

5303

quantity :

25 mg

price :

558 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Wu S, Naar A. SREBP1-dependent de novo fatty acid synthesis gene expression is elevated in malignant melanoma and represents a cellular survival trait. Sci Rep. 2019;9:10369 pubmed publisher

product information

brand :

Tocris

master code :

5303

SKU :

5303/25

product name :

GSK 2194069

description :

Potent human fatty acid synthase (hFASN) inhibitor

target :

Fatty Acid Synthase Inhibitors

category :

Small Molecules

unit size :

25 mg

purity :

99%

observed molecular weight :

428.48

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent human fatty acid synthase (hFASN) inhibitor (IC50 = 7.7 nM); inhibits hFAS -ketoacyl reductase activity. Inhibits lipid synthesis and attenuates proliferation of A549 non-small-cell lung cancer cells (EC50 = 15 nM) in vitro .

catalog number base :

5303

product keywords :

GSK2194069 fatty acid synthases hFAS beta-ketoacyl reductases b-ketoacyl -ketoacyl lipid synthesis inhibitors inhibits Fatty Acid Synthase 5303, FASN

extended description :

Potent human fatty acid synthase (hFASN) inhibitor

chemical name text :

4-[4-(5-Benzofuranyl)phenyl]-5-[[(3S)-1-(cyclopropylcarbonyl)-3-pyrrolidinyl]methyl]-2,4-dihydro-3H-1,2,4-triazol-3-one

formula :

C 25 H 24 N 4 O 3

formula text :

C25H24N4O3

cas num :

1332331-08-4

2020 USD :

531

2021 USD :

558 USD

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage