KYL | Tocris Bioscience 5290/1 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

KYL

catalog :

5290/1

quantity :

1 mg

price :

210 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Defourny J, Peuckert C, Kullander K, Malgrange B. EphA4-ADAM10 Interplay Patterns the Cochlear Sensory Epithelium through Local Disruption of Adherens Junctions. iScience. 2019;11:246-257 pubmed publisher

product information

brand :

Tocris

master code :

5290

SKU :

5290/1

rank :

0.061

product name :

KYL

description :

EphA4 kinase inhibitor; neuroprotective

target :

Eph Receptor Inhibitors

category :

Peptides

sizes available :

1 mg

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=peptides

details of functionality :

KYL is an EphA4 receptor tyrosine kinase inhibitor (Kd = 0.8 M); inhibits EphA4-EphrinA5 interactions (IC50 = 6.34 M). Prevents A O induced synaptic damage, dendritic spine loss and prevents the blocking of LTP in hippocampal CA3-CA1 transmissions. Exhibits a long half life in cell culture media (8 and 12 hours in PC3 and C2C12 media respectively). Neuroprotective.

extended description :

EphA4 kinase inhibitor; neuroprotective

formula :

C 74 H 108 N 14 O 17

formula text :

C74H108N14O17

cas num :

676657-00-4

USD :

210 USD

product details :

EphA4 kinase inhibitor; neuroprotective

storage :

Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

more info or order :

Tocris Bioscience product webpage