OF 1 | Tocris Bioscience 5289/10 product information

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product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

OF 1

catalog :

5289/10

quantity :

10 mg (also 50 mg)

price :

226 USD

product information

brand :

Tocris, a Bio-Techne Brand

catalog number base :

5289

SKU :

5289/10

product name :

OF 1

Description :

Selective BRPF1B and BRPF2 inhibitor

target :

Bromodomain Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

440.31

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

OF 1 is a selective BRPF1B and BRPF2 bromodomain inhibitor (Kd values are 100 and 500 nM respectively). Exhibits 39-fold selectivity for BRPF1B and BRPF2 over BRD4. Accelerates FRAP recovery at 5 M in a BRPF2 FRAP assay. Inhibits RANKL-induced differentiation of primary murine bone marrow cells and human primary monocytes into osteoclasts.

extended description :

Selective BRPF1B and BRPF2 inhibitor

chemical name text :

4-Bromo-N-(2,3-dihydro-6-methoxy-1,3-dimethyl-2-oxo-1H-benzimidazol-5-yl)-2-methylbenzenesulfonamide

formula :

C 17 H 18 BrN 3 O 4 S

formula text :

C17H18BrN3O4S

cas num :

919973-83-4

USD :

226 USD

product details :

Selective BRPF1B and BRPF2 inhibitor

storage :

Store at +4°C