TC-S 7010 | Tocris Bioscience 5286/10 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

TC-S 7010

catalog :

5286/10

quantity :

10 mg (also 50 mg)

price :

273 USD

citations: 1

Reference
Pejskova P, Reilly M, Bino L, Bernatik O, Dolanska L, Ganji R, et al. KIF14 controls ciliogenesis via regulation of Aurora A and is important for Hedgehog signaling. J Cell Biol. 2020;219: pubmed publisher

product information

brand :

Tocris, a Bio-Techne Brand

catalog number base :

5286

SKU :

5286/10

product name :

TC-S 7010

Description :

Potent and selective Aurora kinase A inhibitor

target :

Aurora Kinase Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

99%

observed molecular weight :

588.07

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

TC-S 7010 is a potent and selective inhibitor of Aurora kinase A (IC50 = 3.4 nM); exhibits 1000-fold selectivity for Aurora kinase A over Aurora kinase B. Displays antiproliferative activity in HCT116 and HT29 cells (IC50 values are 0.19 and 2.9 M respectively).

extended description :

Potent and selective Aurora kinase A inhibitor

chemical name text :

N-(2-Chlorophenyl)-4-[[2-[[4-[2-(4-ethyl-1-piperazinyl)-2-oxoethyl]phenyl]amino]-5-fluoro-4-pyrimidinyl]amino]-benzamide

formula :

C 31 H 31 ClFN 7 O 2

formula text :

C31H31ClFN7O2

cas num :

1158838-45-9

USD :

273 USD

product details :

Potent and selective Aurora kinase A inhibitor

storage :

Store at +4°C