HLM 006474 | Tocris Bioscience 5283 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

HLM 006474

catalog :

5283

quantity :

10 mg (also 50 mg)

price :

144 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Dong X, Hu X, Chen J, Hu D, Chen L. BRD4 regulates cellular senescence in gastric cancer cells via E2F/miR-106b/p21 axis. Cell Death Dis. 2018;9:203 pubmed publisher

product information

brand :

Tocris

master code :

5283

SKU :

5283/10

product name :

HLM 006474

description :

E2F transcription factor inhibitor

target :

Additional Transcription Factor Compounds

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

399.48

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

E2F transcription factor inhibitor; inhibits E2F DNA binding activity. Inhibits E2F4 DNA binding and reduces E2F4 protein levels in A375 melanoma cells. Induces apoptosis of A375 and MDA-MB-231 breast cancer cells. Inhibits A375 proliferation and invasion in a three dimensional skin model of A375 invasion. Also attenuates human embryonic stem cell proliferation.

catalog number base :

5283

product keywords :

HLM006474 E2F transcription factors inhibits inhibitors DNA binding A375 melanoma stems cells proliferation human embryonic Other Transcription Factors Stem Cell Proliferation 5283,

extended description :

E2F transcription factor inhibitor

chemical name text :

7-[(4-Ethoxy-3-methylphenyl)(2-pyridinylamino)methyl]-2-methyl-8-quinolinol

formula :

C 25 H 25 N 3 O 2

formula text :

C25H25N3O2

cas num :

353519-63-8

2020 USD :

144

2021 USD :

144 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage