AC 5216 | Tocris Bioscience 5281 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

AC 5216

catalog :

5281

quantity :

10 mg (also 50 mg)

price :

182 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

5281

SKU :

5281/10

product name :

AC 5216

description :

Selective TSPO ligand

target :

Translocator Protein Ligands

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

401.46

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Ligand of translocator protein (TSPO, peripheral benzodiazepine receptor). Exhibits high affinity for TSPO in rat whole brain (Ki = 0.297 nM), and high potency against human and rat glial TSPO (IC50 values are 2.73 and 3.04 nM respectively). Displays no noticeable binding to a number of other receptors, transporters or ion channels. Also displays anxiolytic and antidepressant effects in rodent models, without inducing benzodiazepine-like adverse effects.

catalog number base :

5281

product keywords :

AC5216 anxiolytic anti-anxiety antidepressant mitochondrial benzodiazepine BZD ligands PBR TSPO GABAA XBD173 Translocator Protein 5281,

extended description :

Selective TSPO ligand

chemical name text :

N-Ethyl-7,8-dihydro-7-methyl-8-oxo-2-phenyl-N-(phenylmethyl)-9H-purine-9-acetamide

formula :

C 23 H 23 N 5 O 2

formula text :

C23H23N5O2

cas num :

226954-04-7

2020 USD :

178

2021 USD :

182 USD

alt names :

XBD173

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage