AC 5216 | Tocris Bioscience 5281/50 product information

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product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

AC 5216

catalog :

5281/50

quantity :

50 mg

price :

715 USD

product information

CHEMISTRY :

O=C(N1C)N(CC(N(CC)CC2=CC=CC=C2)=O)C3=C1C=NC(C4=CC=CC=C4)=N3

Stock Reference :

5281/50

Cat Number :

5281

Product Name :

AC 5216

Cas Number :

[226954-04-7]

Unit Size :

50 mg

Size :

Unit :

USD :

715 USD

Primary Category :

Other Pharmacology

Secondary Category :

Translocator Protein

Primary Action :

Selective TSPO ligand

Biological Description :

Ligand of translocator protein (TSPO, peripheral benzodiazepine receptor). Exhibits high affinity for TSPO in rat whole brain (Ki = 0.297 nM), and high potency against human and rat glial TSPO (IC50 values are 2.73 and 3.04 nM respectively). Displays no noticeable binding to a number of other receptors, transporters or ion channels. Also displays anxiolytic and antidepressant effects in rodent models, without inducing benzodiazepine-like adverse effects.

Storage :

Store at +4°C

Formula :

C23H23N5O2

Molwt :

401.46

Minimum Purity :

> 98%

Solubility :

Soluble to 100 mM in DMSO and to 10 mM in ethanol with sonication

RTECS No :

UO7100000

Synonyms :

XBD173