AC 5216 | Tocris Bioscience 5281/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

AC 5216

catalog :

5281/10

quantity :

10 mg (also 50 mg)

price :

230 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 5281 - AC 5216 C23H23N5O2 CAS No. 226954-04-7

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

5281

SKU :

5281/10

product name :

AC 5216

description :

Selective TSPO ligand

target :

Translocator Protein Ligands

unit size :

10 mg (also 50 mg)

category :

Small Molecules

purity :

98%

storage :

Store at +4°C

observed molecular weight :

401.46

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

AC 5216 is a ligand of translocator protein (TSPO, peripheral benzodiazepine receptor). Exhibits high affinity for TSPO in rat whole brain (Ki = 0.297 nM), and high potency against human and rat glial TSPO (IC50 values are 2.73 and 3.04 nM respectively). Displays no noticeable binding to a number of other receptors, transporters or ion channels. Also displays anxiolytic and antidepressant effects in rodent models, without inducing benzodiazepine-like adverse effects.

product keywords :

AC5216 anxiolytic anti-anxiety antidepressant depression mitochondrial benzodiazepine BZD ligands PBR TSPO GABAA XBD173 Translocator Protein 5281,

extended description :

Selective TSPO ligand

chemical name text :

N-Ethyl-7,8-dihydro-7-methyl-8-oxo-2-phenyl-N-(phenylmethyl)-9H-purine-9-acetamide

formula :

C23H23N5O2

formula text :

C23H23N5O2

cas num :

226954-04-7

USD :

227

USD 2025 :

230 USD

product details :

Selective TSPO ligand

alt names :

XBD173

more info or order :

Tocris Bioscience product webpage