IWP 12 | Tocris Bioscience 5279/10 product information

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product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

IWP 12

catalog :

5279/10

quantity :

10 mg (also 50 mg)

price :

188 USD

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

5279

SKU :

5279/10

product name :

IWP 12

description :

Potent PORCN inhibitor; active in vivo

target :

PORCN Inhibitors

unit size :

10 mg (also 50 mg)

category :

Small Molecules

purity :

98%

storage :

Store at +4°C

observed molecular weight :

418.56

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

IWP 12 is a potent inhibitor of Porcupine (PORCN), a membrane-bound O-acyltransferase (MBOAT) (IC50 = 15 nM). Inhibits Wnt/ -catenin and Wnt/planar cell polarity (PCP) signaling pathways. Blocks zebrafish tailfin regeneration in vivo .

product keywords :

IWP12 potent porcupine porcn wnt bcatenin beta_catenin catenin MBOAT membrane-bound O-acyltransferases PORCN 5279,

extended description :

Potent PORCN inhibitor; active in vivo

chemical name text :

N-(6-Methyl-2-benzothiazolyl)-2-[(3,4,6,7-tetrahydro-3,6-dimethyl-4-oxothieno[3,2-d]pyrimidin-2-yl)thio]acetamide

formula :

C18H18N4O2S3

formula text :

C18H18N4O2S3

cas num :

688353-45-9

USD :

208

USD 2025 :

188 USD

product details :

Potent PORCN inhibitor; active in vivo