NS 19504 | Tocris Bioscience 5276/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

NS 19504

catalog :

5276/10

quantity :

10 mg (also 50 mg)

price :

144 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 5276 - NS 19504 C10H9BrN2S CAS No. 327062-46-4

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

5276

SKU :

5276/10

product name :

NS 19504

description :

KCa1.1 (BK) channel activator

target :

Ca2+-Activated Potassium Channel Activators

unit size :

10 mg (also 50 mg)

category :

Small Molecules

purity :

99%

storage :

Store at +4°C

observed molecular weight :

269.16

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

NS 19504 is a selective activator of large-conductance Ca2+-activated potassium channels (BKCa, KCa1.1) (EC50 = 11 M). Activates BK channels in native smooth muscle cells from guinea pig bladder and reduces spontaneous phasic contractions in bladder strips ex vivo . Displays no effect on contractions induced by a high K+ concentration or at 65 other receptors tested, including L- and N- type Ca2+ channels, Nav, KATP and hERG channels.

product keywords :

NS19504 activators large conductance calcium Ca2+-activated potassium channels BKCa, KCa1.1 Ca2+-Activated Potassium Channels 5276,

extended description :

KCa1.1 (BK) channel activator

chemical name text :

5-[(4-Bromophenyl)methyl]-2-thiazolamine

formula :

C10H9BrN2S

formula text :

C10H9BrN2S

cas num :

327062-46-4

USD :

142

USD 2025 :

144 USD

product details :

KCa1.1 (BK) channel activator

more info or order :

Tocris Bioscience product webpage