LSN 2463359 | Tocris Bioscience 5275/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

LSN 2463359

catalog :

5275/10

quantity :

10 mg (also 50 mg)

price :

181 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 5275 - LSN 2463359 C16H15N3O CAS No. 1401031-52-4

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

5275

SKU :

5275/10

product name :

LSN 2463359

description :

Potent and selective positive allosteric modulator of mGlu5 receptors

target :

Group I mGluR Modulators

unit size :

10 mg (also 50 mg)

category :

Small Molecules

purity :

99%

storage :

Store at +4°C

observed molecular weight :

265.31

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

LSN 2463359 is a potent and selective positive allosteric modulator at the mGlu5 receptor (EC50 = 24 nM). Has no activity at mGlu1-4, mGlu8 and GABAB receptors. Reverses methylazoxymethanol acetate (MAM)-induced deficits in reversal learning memory and normalizes SDZ 220-581 and RO 63-1908 -induced alterations in instrumental responses in rat models. Promotes wakefulness in vivo . Brain penetrant and orally active.

product keywords :

LSN2463359 potent selective positive allosteric modulator PAM MGLU5 brain penetrant orally active schizophrenia Glutamate (Metabotropic) Group I Receptors 5275,

extended description :

Potent and selective positive allosteric modulator of mGlu5 receptors

chemical name text :

N-(1-Methylethyl)-5-[2-(4-pyridinyl)ethynyl]-2-pyridinecarboxamide

formula :

C16H15N3O

formula text :

C16H15N3O

cas num :

1401031-52-4

USD :

179

USD 2025 :

181 USD

product details :

Potent and selective positive allosteric modulator of mGlu5 receptors

more info or order :

Tocris Bioscience product webpage