product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
UNC 3230
catalog :
5271/10
quantity :
10 mg (also 50 mg)
price :
241 USD
more info or order :
citations: 1
Reference
Peng W, Huang W, Ge X, Xue L, Zhao W, Xue J. Type Iγ phosphatidylinositol phosphate kinase promotes tumor growth by facilitating Warburg effect in colorectal cancer. EBioMedicine. 2019;: pubmed publisher
product information
brand :
Tocris
master code :
5271
SKU :
5271/10
rank :
0.061
product name :
UNC 3230
description :
Potent and selective PIP5K1C inhibitor; antinociceptive
target :
Other Kinase Inhibitors
category :
Small Molecules
sizes available :
10 mg (also 50 mg)
url print :
?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
UNC 3230 is a potent and selective PIP5K1C inhibitor (IC50 = 41 nM). Exhibits selectivity for PIP5K1C over PIP5K1A, the PI 3-kinase family and a panel of other kinases. Reduces PIP2 levels and LPA-induced calcium signaling in dorsal root ganglia (DRG) neurons in vitro . Reduces nociception in mouse models of chronic pain.
extended description :
Potent and selective PIP5K1C inhibitor; antinociceptive
chemical name text :
5-[(Cyclohexylcarbonyl)amino]-2-(phenylamino)-thiazolecarboxamide
formula :
C 17 H 20 N 4 O 2 S
formula text :
C17H20N4O2S
cas num :
1031602-63-7
USD :
241 USD
product details :
Potent and selective PIP5K1C inhibitor; antinociceptive
storage :
Store the unopened product at 2 - 8 °C. Do not use past expiration date.
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK