OICR 9429 | Tocris Bioscience 5267 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

OICR 9429

catalog :

5267

quantity :

10 mg (also 50 mg)

price :

217 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

5267

SKU :

5267/10

product name :

OICR 9429

description :

High affinity and selective WDR5 antagonist

target :

Lysine Methyltransferase Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

555.59

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

High affinity WDR5 antagonist (Kd = 93 nM; IC50 = 64 nM); disrupts WDR5-MLL interaction. Exhibits selectivity for WDR5 over 22 methyltransferases and a panel of kinases, GPCRs, ion channels, and transporters. Reduces viability of acute myeloid leukemia cells in vitro . Also disrupts MLL1-RbBP5 interaction. . To request the negative control for OICR 9429, please fill out the OICR 0547 request form on the SGC website.

catalog number base :

5267

product keywords :

OICR9429 High affinity selective WDR5 antagonists WD repeat-containing proteins 5 antagonism sgc Lysine Methyltransferases WDR5 5267,

extended description :

High affinity and selective WDR5 antagonist

chemical name text :

N-[2-(4-Methylpiperazin-1-yl)-5-[3-(morpholin-4-ylmethyl)phenyl]phenyl]-6-oxo-4-(trifluoromethyl)-1,6-dihydropyridine-3-carboxamide

formula :

C 29 H 32 F 3 N 5 O 3

formula text :

C29H32F3N5O3

cas num :

1801787-56-3

2020 USD :

210

2021 USD :

217 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage