product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
SSM 3 trifluoroacetate
catalog :
5253/10
quantity :
10 mg
price :
335 USD
more info or order :
citations: 4
Reference
Dicenta V, Pelzer A, Laspa Z, Castor T, Gawaz M, Rohlfing A. The subtilisin-like protease furin regulates hemin-induced CD63 surface expression on platelets. Biochem Biophys Res Commun. 2024;701:149629 pubmed publisher
Hervouet K, Ferri xe9 M, Ankavay M, Montpellier C, Camuzet C, Alexandre V, et al. An Arginine-Rich Motif in the ORF2 capsid protein regulates the hepatitis E virus lifecycle and interactions with the host cell. PLoS Pathog. 2022;18:e1010798 pubmed publisher
Reichmann M, Tezera L, Vallejo A, Vukmirovic M, Xiao R, Reynolds J, et al. Integrated transcriptomic analysis of human tuberculosis granulomas and a biomimetic model identifies therapeutic targets. J Clin Invest. 2021;131: pubmed publisher
Cheng Y, Chao T, Li C, Chiu M, Kao H, Wang S, et al. Furin Inhibitors Block SARS-CoV-2 Spike Protein Cleavage to Suppress Virus Production and Cytopathic Effects. Cell Rep. 2020;33:108254 pubmed publisher
image
image 1 :
Tocris Bioscience 5253/10 image 1
Cat.No. 5253 - SSM 3 trifluoroacetate C22H32N12O2.4CF3CO2H CAS No. 2320930-10-5
product information
brand :
Tocris, a Bio-Techne brand
catalog number base :
5253
SKU :
5253/10
product name :
SSM 3 trifluoroacetate
description :
Potent furin inhibitor
target :
Furin Inhibitors
unit size :
10 mg
category :
Small Molecules
purity :
98%
storage :
Store at -20°C
observed molecular weight :
952.66
url print :
?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
SSM 3 trifluoroacetate is a potent furin inhibitor (EC50 = 54 nM). Blocks furin-dependent cell surface processing of anthrax protective antigen-83 in vitro .
product keywords :
SSM3 SSM 3 trifluoroacetate furin inhibitors inhibits SSM-3 922732-52-3 Furin 5253, bioprocessingenzymes, Proprotein Convertase, Serine Protease, Proprotein Convertase Subtilisin/Kexin Type 3, FES Upstream Region, Dibasic Processing Enzyme, Golgi Apparatus Markers
extended description :
Potent furin inhibitor
chemical name text :
rel-N,N -[[(1R,3S,4S,6R)-4,6-Bis[(aminoiminomethyl)amino]-1,3-cyclohexanedyil]bis(oxy-4,1-phenylene)]bisguanidine tetratrifluoroacetate salt
formula :
C22H32N12O2.4CF3CO2H
formula text :
C22H32N12O2.4CF3CO2H
cas num :
2320930-10-5
USD :
331
USD 2025 :
335 USD
product details :
Potent furin inhibitor
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK