XAP 044 | Tocris Bioscience 5248 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

XAP 044

catalog :

5248

quantity :

10 mg (also 50 mg)

price :

203 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

5248

SKU :

5248/10

product name :

XAP 044

description :

Potent and selective mGlu7 antagonist

target :

Group III mGluR Antagonists

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

380.13

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent and selective mGlu7 antagonist (IC50 = 88 nM); inhibits lateral amygdala long term potentiation (LTP) in brain slices from wild type mice. Displays no effects on the LTP of mGlu7 deficient mice. Exhibits novel activity by binding to the mGlu7 Venus flytrap domain (VFTD). Exhibits anti-anxiety effects in rodent models. Brain penetrant.

catalog number base :

5248

product keywords :

XAP044 potent specific mGlu7 antagonists glutamate metabotropic group III receptors venus flytrap domain VFTD anti-anxiety Brain penetrant Glutamate (Metabotropic) Group III Receptors 5248,

extended description :

Potent and selective mGlu7 antagonist

chemical name text :

7-Hydroxy-3-(4-iodophenoxy)-4H-1-benzopyran-4-one

formula :

C 15 H 9 IO 4

formula text :

C15H9IO4

cas num :

196928-50-4

2020 USD :

203

2021 USD :

203 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage