NVP ADW 742 | Tocris Bioscience 5247/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

NVP ADW 742

catalog :

5247/10

quantity :

10 mg (also 50 mg)

price :

218 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 5247 - NVP ADW 742 C28H31N5O CAS No. 475488-23-4

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

5247

SKU :

5247/10

product name :

NVP ADW 742

description :

ATP-competitive inhibitor of IGF1R

target :

Insulin and Insulin-like Receptor Inhibitors

unit size :

10 mg (also 50 mg)

category :

Small Molecules

purity :

99%

storage :

Store at -20°C

observed molecular weight :

453.58

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

NVP ADW 742 is an ATP-competitive inhibitor of IGF1R (IC50 in the range of 0.1-0.2 M). Also inhibits c-Kit kinase activity (IC50 in the range of 3-5 M). Exhibits a synergistic effect with Imatinib (Cat. No. 5906), enhancing the sensitivity of multiple small cell lung cancer cell lines to the chemotherapeutics Etoposide (Cat. No. 1226) and Carboplatin (Cat. No. 2626).

product keywords :

NVPADW742 ATP competitive inhibitors inhibits of IGF1 receptors kinases c-Kit small cell lung cancer cell lines SCLC insulin-like growth factor-1 receptor Insulin and insulin-like Receptors Insulin and Insulin-like Receptors 5247,

extended description :

ATP-competitive inhibitor of IGF1R

chemical name text :

5-[3-(Phenylmethoxy)phenyl]-7-[trans-3-(1-pyrrolidinylmethyl)cyclobutyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine

formula :

C28H31N5O

formula text :

C28H31N5O

cas num :

475488-23-4

USD :

242

USD 2025 :

218 USD

product details :

ATP-competitive inhibitor of IGF1R

more info or order :

Tocris Bioscience product webpage