Ebselen | Tocris Bioscience 5245/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Ebselen

catalog :

5245/10

quantity :

10 mg (also 50 mg)

price :

99 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Kuschak M, Namasivayam V, Rafehi M, Voss J, Garg J, Schlegel J, et al. Cell-permeable high-affinity tracers for Gq proteins provide structural insights, reveal distinct binding kinetics and identify small molecule inhibitors. Br J Pharmacol. 2020;177:1898-1916 pubmed publisher

product information

brand :

Tocris

master code :

5245

SKU :

5245/10

rank :

0.061

product name :

Ebselen

description :

Glutathione peroxidase mimic; peroxynitrite scavenger

target :

Additional Antioxidant Compounds

category :

Small Molecules

sizes available :

10 mg (also 50 mg)

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Ebselen is a glutathione peroxidase mimic; peroxynitrite scavenger. Inhibits ferroptosis. Also inhibits lipoxygenase, cyclooxygenase, nitric oxide synthase, protein kinase C and H+/K+-ATPase activity. Inhibits the hepatic carcinogenic effects of aflatoxin B1. Antioxidant and anti-inflammatory. Selectively inhibits Gq protein signaling and enhances differentiation of brown adipocytes. Inhibits SARS-CoV-2 Mpro in vitro (IC50 = 0.67 M in FRET assay)

extended description :

Glutathione peroxidase mimic; peroxynitrite scavenger

chemical name text :

2-Phenyl-1,2-benzisoselenazol-3(2H)-one

formula :

C 13 H 9 NOSe

formula text :

C13H9NOSe

cas num :

60940-34-3

USD :

99 USD

product details :

Glutathione peroxidase mimic; peroxynitrite scavenger

storage :

Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

more info or order :

Tocris Bioscience product webpage