CCG 1423 | Tocris Bioscience 5233/10 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

CCG 1423

catalog :

5233/10

quantity :

10 mg (also 50 mg)

price :

141 USD

citations: 4

Reference
Liu L, Bankell E, Rippe C, Mor xe9 n B, Stenkula K, Nilsson B, et al. Cell Type Dependent Suppression of Inflammatory Mediators by Myocardin Related Transcription Factors. Front Physiol. 2021;12:732564 pubmed publisher
Liu L, Rippe C, Hansson O, Kryvokhyzha D, Fisher S, Ekman M, et al. Regulation of the Muscarinic M3 Receptor by Myocardin-Related Transcription Factors. Front Physiol. 2021;12:710968 pubmed publisher
Bakovic A, Bhalla N, Alem F, Campbell C, Zhou W, Narayanan A. Inhibitors of Venezuelan Equine Encephalitis Virus Identified Based on Host Interaction Partners of Viral Non-Structural Protein 3. Viruses. 2021;13: pubmed publisher
Gopalakrishnan R, Matta H, Choi S, Chaudhary P. Narciclasine, an isocarbostyril alkaloid, has preferential activity against primary effusion lymphoma. Sci Rep. 2020;10:5712 pubmed publisher

product information

brand :

Tocris, a Bio-Techne Brand

catalog number base :

5233

SKU :

5233/10

product name :

CCG 1423

Description :

Rho/SRF pathway inhibitor; induces intermediate mesoderm differentiation from ESCs

target :

Rho GTPase Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

99%

observed molecular weight :

454.75

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

CCG 1423 is a Rho/SRF pathway inhibitor; stimulates apoptosis of a melanoma cell line overexpressing RhoC (A375M2). Suppresses Rho-dependent invasion of PC-3 prostate cancer cells in vitro and inhibits lysophosphatidic acid-induced DNA synthesis in PC-3 prostate cancer cells. When used in combination with Retinoic acid, LY 294002 and Pyridone 6, it induces intermediate mesoderm differentiation from ESCs.

extended description :

Rho/SRF pathway inhibitor; induces intermediate mesoderm differentiation from ESCs

chemical name text :

N-[2-[(4-Chlorophenyl)amino]-1-methyl-2-oxoethoxy]-3,5-bis(trifluoromethyl)benzamide

formula :

C 18 H 13 ClF 6 N 2 O 3

formula text :

C18H13ClF6N2O3

cas num :

285986-88-1

USD :

141 USD

product details :

Rho/SRF pathway inhibitor; induces intermediate mesoderm differentiation from ESCs

storage :

Store at +4°C