AZ 191 | Tocris Bioscience 5232 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

AZ 191

catalog :

5232

quantity :

10 mg (also 50 mg)

price :

199 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Blake D, Vaseva A, Hodge R, Kline M, Gilbert T, Tyagi V, et al. Application of a MYC degradation screen identifies sensitivity to CDK9 inhibitors in KRAS-mutant pancreatic cancer. Sci Signal. 2019;12: pubmed publisher

product information

brand :

Tocris

master code :

5232

SKU :

5232/10

product name :

AZ 191

description :

Potent DYRK1B inhibitor

target :

DYRK Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

429.52

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent DYRK1B inhibitor (IC50 values are 17, 88 and 1890 nM for DYRK1B, DYRK1A and DYRK2 respectively). Inhibits DYRK1B-induced Gi phase cell cycle arrest in Panc-1 cells in vitro .

catalog number base :

5232

product keywords :

AZ191 potent dyrk1b dual specificity tyrosine phosphorylation regulated kinases inhibitors inhibits DYRK 5232,

extended description :

Potent DYRK1B inhibitor

chemical name text :

N-[2-Methoxy-4-(4-methyl-1-piperazinyl)phenyl]-4-(1-methyl-1H-pyrrolo[2,3-c]pyridin-3-yl)-2-pyrimidinamine

formula :

C 24 H 27 N 7 O

formula text :

C24H27N7O

cas num :

1594092-37-1

2020 USD :

195

2021 USD :

199 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage