MPC 6827 hydrochloride | Tocris Bioscience 5231/10 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

MPC 6827 hydrochloride

catalog :

5231/10

quantity :

10 mg (also 50 mg)

price :

261 USD

citations: 2

Reference
Damuka N, Orr M, Bansode A, Krizan I, Miller M, Lee J, et al. Preliminary mechanistic insights of a brain-penetrant microtubule imaging PET ligand in a tau-knockout mouse model. EJNMMI Res. 2022;12:41 pubmed publisher
Damuka N, Martin T, Bansode A, Krizan I, Martin C, Miller M, et al. Initial Evaluations of the Microtubule-Based PET Radiotracer, [11C]MPC-6827 in a Rodent Model of Cocaine Abuse. Front Med (Lausanne). 2022;9:817274 pubmed publisher

product information

brand :

Tocris, a Bio-Techne Brand

catalog number base :

5231

SKU :

5231/10

product name :

MPC 6827 hydrochloride

Description :

Inhibitor of microtubule polymerization; antimitotic and antitumor

target :

Microtubule Binding Compounds

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

315.8

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

MPC 6827 hydrochloride is a potent inhibitor of microtubule formation (IC50 = 1.5 - 3.4 nM); inhibits polymerization of tubulin in vitro and disrupts microtubule formation in several cancer cell lines. Inhibits tumor growth in vitro and in vivo ; exhibits pro-apoptotic characteristics. Brain penetrant.

extended description :

Inhibitor of microtubule polymerization; antimitotic and antitumor

chemical name text :

N-(4-Methoxyphenyl)-N,2-dimethyl-4-quinazolinamine hydrochloride

formula :

C 17 H 17 N 3 O.HCl

formula text :

C17H17N3O.HCl

cas num :

917369-31-4

USD :

261 USD

product details :

Inhibitor of microtubule polymerization; antimitotic and antitumor

storage :

Desiccate at RT