IWP 4 | Tocris Bioscience 5214 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

IWP 4

catalog :

5214

quantity :

10 mg (also 50 mg)

price :

212 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Sewanan L, Schwan J, Kluger J, Park J, Jacoby D, Qyang Y, et al. Extracellular Matrix From Hypertrophic Myocardium Provokes Impaired Twitch Dynamics in Healthy Cardiomyocytes. JACC Basic Transl Sci. 2019;4:495-505 pubmed publisher
Moghadasi Boroujeni S, KOONTZ A, Tseropoulos G, Kerosuo L, Mehrotra P, Bajpai V, et al. Neural crest stem cells from human epidermis of aged donors maintain their multipotency in vitro and in vivo. Sci Rep. 2019;9:9750 pubmed publisher

product information

brand :

Tocris

master code :

5214

SKU :

5214/10

product name :

IWP 4

description :

Potent inhibitor of Wnt/ -catenin signaling

target :

beta-Catenin Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

496.62

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent inhibitor of Wnt/ -catenin signaling (IC50 = 25 nM). Has minimal effect on Notch and Hedgehog signaling pathways. Induces differentiation of cardiomyocytes from human ESCs and iPSCs.

catalog number base :

5214

product keywords :

IWP4 potent inhibitors inhibits Wnt beta-catenin -catenin b-catenin cardiomyocytes ESCs iPSCs stem cells embryonic pluripotent differentiation Beta-catenin Cardiomyocyte Stem Cells ESCs and iPSC Organoids 5214,

extended description :

Potent inhibitor of Wnt/ -catenin signaling

chemical name text :

N-(6-Methyl-2-benzothiazolyl)-2-[(3,4,6,7-tetrahydro-3-(2-methoxyphenyl)-4-oxothieno[3,2-d]pyrimidin-2-yl)thio]-acetamide

formula :

C 23 H 20 N 4 O 3 S 3

formula text :

C23H20N4O3S3

cas num :

686772-17-8

2020 USD :

203

2021 USD :

212 USD

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage