chemical

LL 37

5213/1

1 mg

370 USD

5213

5213/1

0.061

LL 37

Antimicrobial peptide derivative of human cathelicidin

Miscellaneous Compounds

Peptides

1 mg

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LL 37 is an antimicrobial peptide derivative of human cathelicidin. Induces FPRL1-mediated chemotaxis of human neutrophils, monocytes and T cells in vitro . Promotes wound healing following skin-targeted electroporation of a plasmid encoding hCAP-18/LL-37 in mice. LL 37 reduces SARS-CoV-2 infection by blocking the receptor binding domain of the S1 spike protein (Kd = 11.2 nM) and by binding to ACE2 (Kd = 25.5.nM). LL 37 inhibits SARS-CoV-2 pseudovirion infection (IC50 = 4.74 g/mL) in vitro and in vivo . Also triggers apoptosis in colon cancer cells. Cell permeable.

Antimicrobial peptide derivative of human cathelicidin

C 205 H 34 0N 60 O 53

C205H340N60O53

154947-66-7

370 USD

Antimicrobial peptide derivative of human cathelicidin

Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.