AZD 7762 hydrochloride | Tocris Bioscience 5199/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

AZD 7762 hydrochloride

catalog :

5199/10

quantity :

10 mg (also 50 mg)

price :

259 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 5199 - AZD 7762 hydrochloride C17H19FN4O2S.HCl CAS No. 1246094-78-9

product information

brand :

Tocris

master code :

5199

SKU :

5199/10

rank :

0.061

product name :

AZD 7762 hydrochloride

description :

Potent and selective ATP-competitive inhibitor of Chk1 and Chk2; also enhances CRISPR-Cpf1-mediated genome editing

target :

Checkpoint Kinase Inhibitors

category :

Small Molecules

sizes available :

10 mg (also 50 mg)

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

AZD 7762 hydrochloride is a potent and selective ATP-competitive inhibitor of Chk1 and Chk2 (IC50 vales are 5 nM for both kinases); displays at least 10 fold selectivity over a panel of 164 kinases. Potentiates cytotoxicity of DNA-damaging agents. Active in vivo . Also improves efficiency of CRISPR-Cpf1-mediated genome editing in hPSC lines (2.7-fold at 1 M).

extended description :

Potent and selective ATP-competitive inhibitor of Chk1 and Chk2; also enhances CRISPR-Cpf1-mediated genome editing

chemical name text :

3-[(Aminocarbonyl)amino]-5-(3-fluorophenyl)-N-(3S)-3-piperidinyl-2-thiophenecarboxamide hydrochloride

formula :

C 17 H 19 FN 4 O 2 S.HCl

formula text :

C17H19FN4O2S.HCl

cas num :

1246094-78-9

USD :

259 USD

product details :

Potent and selective ATP-competitive inhibitor of Chk1 and Chk2; also enhances CRISPR-Cpf1-mediated genome editing

storage :

Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

more info or order :

Tocris Bioscience product webpage