chemical

Spautin 1

5197

10 mg (also 50 mg)

150 USD

5197

5197/10

Spautin 1

USP10 and USP13 inhibitor; inhibits autophagy

Deubiquitinating Enzyme Inhibitors

Small Molecules

10 mg (also 50 mg)

98%

271.26

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

Inhibitor of autophagy; inhibits USP10 and USP13 activity (IC50 values are 0.6 and 0.7 M respectively) and promotes degradation of Vps34 (class III PI 3-kinase) complexes. Selectively promotes apoptosis of cancer cells under starvation conditions. Prevents the PDGF-induced conversion from the contractile to synthetic phenotype in vascular smooth muscle cells.

5197

class III PI3 kinase autophagy inhibitors inhibits USP10 USP13 deubiquitinating enzymes vps34 Deubiquitinating Enzymes Autophagy 5197,, DUB, Deubiquitinase

USP10 and USP13 inhibitor; inhibits autophagy

6-Fluoro-N-[(4-Fluorophenyl)methyl]-4-quinazolinamine

C 15 H 11 F 2 N 3

C15H11F2N3

1262888-28-7

145

150 USD

Store at +4°C