Spautin 1 | Tocris Bioscience 5197/50 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Spautin 1

catalog :

5197/50

quantity :

50 mg

price :

644 USD

product information

brand :

Tocris

master code :

5197

SKU :

5197/50

product name :

Spautin 1

description :

USP10 and USP13 inhibitor; inhibits autophagy

target :

Deubiquitinating Enzyme Inhibitors

category :

Small Molecules

unit size :

50 mg

purity :

98%

observed molecular weight :

271.26

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Spautin 1 is an inhibitor of autophagy; inhibits USP10 and USP13 activity (IC50 values are 0.6 and 0.7 M respectively) and promotes degradation of Vps34 (class III PI 3-kinase) complexes. Selectively promotes apoptosis of cancer cells under starvation conditions. Prevents the PDGF-induced conversion from the contractile to synthetic phenotype in vascular smooth muscle cells.

catalog number base :

5197

extended description :

USP10 and USP13 inhibitor; inhibits autophagy

chemical name text :

6-Fluoro-N-[(4-Fluorophenyl)methyl]-4-quinazolinamine

formula :

C 15 H 11 F 2 N 3

formula text :

C15H11F2N3

cas num :

1262888-28-7

USD 2021 :

610

USD 2022 :

644 USD

product details :

USP10 and USP13 inhibitor; inhibits autophagy

storage :

Store at +4°C