product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
NBI 31772
catalog :
5192
quantity :
10 mg (also 50 mg)
price :
219 USD
more info or order :
citations: 1
Reference
Ichijo R, Kobayashi H, Yoneda S, Iizuka Y, Kubo H, Matsumura S, et al. Tbx3-dependent amplifying stem cell progeny drives interfollicular epidermal expansion during pregnancy and regeneration. Nat Commun. 2017;8:508 pubmed publisher
product information
brand :
Tocris
master code :
5192
SKU :
5192/10
product name :
NBI 31772
description :
High affinity insulin-like growth factor-I binding protein IGFBP inhibitor
target :
Insulin and Insulin-like Receptor Inhibitors
category :
Small Molecules
unit size :
10 mg (also 50 mg)
purity :
98%
observed molecular weight :
341.27
url print :
?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
High affinity insulin-like growth factor-1 binding protein (IGFBP) inhibitor (Ki values are 1 - 24 nM for all six human subtypes). Displaces insulin-like growth factor-1 (IGF-1) from the IGF-1:IGFBP complex and suppresses IGF1-induced proliferation of 3T3 fibroblasts. Also increases cardiomyocyte proliferation in vivo .
catalog number base :
5192
product keywords :
NBI31772 High affinity insulin-like growth factor-1 binding proteins inhibitors inhibits IGFBP-3 IGF-1 cardiomyocytes Insulin and insulin-like Receptors Insulin and Insulin-like Receptors 5192,
extended description :
High affinity insulin-like growth factor-I binding protein IGFBP inhibitor
chemical name text :
1-(3,4-Dihydroxybenzoyl)-6,7-dihydroxy-3-isoquinolinecarboxylic acid
formula :
C 17 H 11 NO 7
formula text :
C17H11NO7
cas num :
374620-70-9
2020 USD :
214
2021 USD :
219 USD
storage :
Store at -20°C
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK