NBI 31772 | Tocris Bioscience 5192/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

NBI 31772

catalog :

5192/10

quantity :

10 mg (also 50 mg)

price :

255 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Ichijo R, Kobayashi H, Yoneda S, Iizuka Y, Kubo H, Matsumura S, et al. Tbx3-dependent amplifying stem cell progeny drives interfollicular epidermal expansion during pregnancy and regeneration. Nat Commun. 2017;8:508 pubmed publisher

product information

brand :

Tocris

master code :

5192

SKU :

5192/10

rank :

0.061

product name :

NBI 31772

description :

High affinity insulin-like growth factor-I binding protein IGFBP inhibitor

target :

Insulin and Insulin-like Receptor Inhibitors

category :

Small Molecules

sizes available :

10 mg (also 50 mg)

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

NBI 31772 is a high affinity insulin-like growth factor-1 binding protein (IGFBP) inhibitor (Ki values are 1 - 24 nM for all six human subtypes). Displaces insulin-like growth factor-1 (IGF-1) from the IGF-1:IGFBP complex and suppresses IGF1-induced proliferation of 3T3 fibroblasts. Also increases cardiomyocyte proliferation in vivo .

extended description :

High affinity insulin-like growth factor-I binding protein IGFBP inhibitor

chemical name text :

1-(3,4-Dihydroxybenzoyl)-6,7-dihydroxy-3-isoquinolinecarboxylic acid

formula :

C 17 H 11 NO 7

formula text :

C17H11NO7

cas num :

374620-70-9

USD :

255 USD

product details :

High affinity insulin-like growth factor-I binding protein IGFBP inhibitor

storage :

Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

more info or order :

Tocris Bioscience product webpage