ETP 45835 dihydrochloride | Tocris Bioscience 5183 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

ETP 45835 dihydrochloride

catalog :

5183

quantity :

10 mg (also 50 mg)

price :

208 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Ichiyanagi O, Ito H, Naito S, Kabasawa T, Kanno H, Narisawa T, et al. Impact of eIF4E phosphorylation at Ser209 via MNK2a on tumour recurrence after curative surgery in localized clear cell renal cell carcinoma. Oncotarget. 2019;10:4053-4068 pubmed publisher

product information

brand :

Tocris

master code :

5183

SKU :

5183/10

product name :

ETP 45835 dihydrochloride

description :

Mnk1 and Mnk2 inhibitor

target :

Mnk Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

99%

observed molecular weight :

301.21

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Mnk2 and Mnk1 inhibitor (IC50 values are 575 and 646 nM respectively). Exhibits selectivity against a panel of 24 protein kinases, including those upstream of Mnk1/2.

catalog number base :

5183

product keywords :

ETP45835 dihydrochloride mitogen-activated protein kinase-interacting kinase Mnk1 Mnk2 inhibitors inhibits [791852-46-5] Mnk 5183,

extended description :

Mnk1 and Mnk2 inhibitor

chemical name text :

4-[5-(4-Piperidinyl)-1H-pyrazol-3-yl]pyridine dihydrochloride

formula :

C 13 H 16 N 4 .2HCl

formula text :

C13H16N4.2HCl

2020 USD :

201

2021 USD :

208 USD

storage :

Desiccate at RT

more info or order :

Tocris Bioscience product webpage