ETP 45835 dihydrochloride | Tocris Bioscience 5183/10 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

ETP 45835 dihydrochloride

catalog :

5183/10

quantity :

10 mg (also 50 mg)

price :

258 USD

citations: 1

Reference
Ichiyanagi O, Ito H, Naito S, Kabasawa T, Kanno H, Narisawa T, et al. Impact of eIF4E phosphorylation at Ser209 via MNK2a on tumour recurrence after curative surgery in localized clear cell renal cell carcinoma. Oncotarget. 2019;10:4053-4068 pubmed publisher

product information

brand :

Tocris, a Bio-Techne Brand

catalog number base :

5183

SKU :

5183/10

product name :

ETP 45835 dihydrochloride

Description :

Mnk1 and Mnk2 inhibitor

target :

Mnk Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

99%

observed molecular weight :

301.21

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

ETP 45835 dihydrochloride is a Mnk2 and Mnk1 inhibitor (IC50 values are 575 and 646 nM respectively). Exhibits selectivity against a panel of 24 protein kinases, including those upstream of Mnk1/2.

extended description :

Mnk1 and Mnk2 inhibitor

chemical name text :

4-[5-(4-Piperidinyl)-1H-pyrazol-3-yl]pyridine dihydrochloride

formula :

C 13 H 16 N 4 .2HCl

formula text :

C13H16N4.2HCl

cas num :

2136571-30-5

USD :

258 USD

product details :

Mnk1 and Mnk2 inhibitor

storage :

Desiccate at RT