Tolvaptan | Tocris Bioscience 5181 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Tolvaptan

catalog :

5181

quantity :

10 mg (also 50 mg)

price :

185 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Zeynalov E, Jones S, Seo J, Snell L, Elliott J. Arginine-Vasopressin Receptor Blocker Conivaptan Reduces Brain Edema and Blood-Brain Barrier Disruption after Experimental Stroke in Mice. PLoS ONE. 2015;10:e0136121 pubmed publisher

product information

brand :

Tocris

master code :

5181

SKU :

5181/10

product name :

Tolvaptan

description :

Potent and selective vasopressin V2 receptor antagonist; renoprotective and orally active

target :

Vasopressin Receptor Antagonists

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

448.94

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent and selective competitive vasopressin V2 receptor antagonist (Ki values are 0.06 and 12.3 nM for V2 and V1a receptors respectively). Decreases urine osmolality and increases serum sodium concentrations. Delays the onset of end-stage renal disease in a mouse model of polycystic kidney disease. Exhibits myocardial and renal protective effects in hypertensive heart failure rats. Orally active.

catalog number base :

5181

product keywords :

Tolvaptan potent selective competitive vasopressin receptors antagonists V2 renal cardial protective renoprotective hyponatremia OPC-41061 Vasopressin Receptors 5181,

extended description :

Potent and selective vasopressin V2 receptor antagonist; renoprotective and orally active

chemical name text :

N-[4-[(7-Chloro-2,3,4,5-tetrahydro-5-hydroxy-1H-1-benzazepin-1-yl)carbonyl]-3-methylphenyl]-2-methylbenzamide

formula :

C 26 H 25 ClN 2 O 3

formula text :

C26H25ClN2O3

cas num :

150683-30-0

2020 USD :

176

2021 USD :

185 USD

alt names :

OPC-41061

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage